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These results are consistent with previous meta-analyses that investigated liraglutide and exenatide, as well as post-hoc analyses from the SUSTAIN and PIONEER programs that shown significant CRP reductions with semaglutide ( Additionally, the degree and consistency of CRP decrease with GLP-1 RAs in our head-to-head comparisons reflect different or complementary molecular routes, even though other glucose-lowering medications, such as SGLT2 inhibitors and DPP-4 inhibitors, have shown minor anti-inflammatory benefits

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Antecedentes histricos y contexto cientfico Cientfico El inters por los complejos peptdicos sintticos se ha ampliado considerablemente gracias a los avances en biologa molecular e investigacin bioqumica

10.1016/j.nbd.2016.05.009 Neurobiol